It is indicated in adults for the prevention of acute nausea and vomiting associated with highly emetogenic cancer chemotherapy and for the prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy. It is also used in pediatric patients aged one month and older for the prevention of acute nausea and vomiting associated with highly emetogenic chemotherapy and for the prevention of nausea and vomiting associated with moderately emetogenic chemotherapy.